Cambridge Healthtech Institute’s 4th Annual
Safety and Efficacy of Bispecific and Multispecific Antibodies
Enhancing Safety and Creating Synergies with Novel Therapeutic Modalities
17 November 2026
The evolution of bispecific antibodies is rapidly expanding the therapeutic landscape, moving beyond simple dual-targeting to complex architectures. As new candidates enter the clinic, balancing potent anti-tumour activity with manageable safety profiles remains the central challenge for drug developers. At PEGS Europe, Cambridge Healthtech Institute's Fourth Annual Safety and Efficacy of Bispecific and Multispecific Antibodies program focuses on the performance and clinical risk mitigation of sophisticated molecules. This year's program will highlight emerging clinical-stage candidates and strategies to overcome barriers in the solid tumour microenvironment. Furthermore, the program will explore the safety and synergy of combination regimens, addressing the unique considerations of pairing multispecifics with ADCs and checkpoint inhibitors. This meeting provides a critical forum for bridging the gap between innovative drug development and successful clinical outcomes. The program will complement topics in bispecific antibody discovery and engineering.
Coverage will include, but is not limited to:
- Novel and emerging drug candidates and associated safety and efficacy profiles
- Strategic target-based therapeutic development
- Logic gating for enhanced target selectivity
- Addressing immunogenicity risks and clinical impacts
- Engineering co-stimulation to improve efficacy
- Mitigating tumour resistance and antigen downregulation
- Overcoming challenges in solid tumour penetration
- Data-driven dose optimisation and escalation
- Assessing safety of combination therapies
The deadline for priority consideration is 9 April 2026.
All proposals are subject to review by session chairpersons and/or the Scientific Advisory Committee to ensure the overall quality of the conference program. Additionally, as per Cambridge Healthtech Institute’s policy, a select number of vendors and consultants who provide products and services will be offered opportunities for podium presentation slots based on a variety of Corporate Sponsorships.
Opportunities for Participation: